Political Candidate Personal Responsibility Act of 1999 - Prohibits a candidate for Federal office from receiving the lowest unit charge for advertising on television or radio (offered 45 days before a primary election and 60 days before a general election) unless the candidate certifies that he or she will not make any direct reference to another candidate for the same office, unless: (1) such reference meets requirements of this Act; and (2) a communication which contains such reference also contains a prominently displayed image (television) or the voice (radio) of the candidate during at least 75 percent of the broadcast time.

States that a candidate meets the requirements of this Act if: (1) in the case of a television broadcast, the reference is made by the candidate in a personal appearance on the screen; and (2) in the case of a radio broadcast, the reference is made by the candidate in a personal audio statement during which the candidate and the office are identified.