Enhancement of Privacy and Public Safety in Cyberspace Act - Amends the Federal criminal code to mandate a fine, imprisonment of up to ten years, or both, if an offense or attempted offense in connection with computers would or could cause: (1) loss to one or more persons during any one year period of at least $5,000; (2) modification or impairment of medical examination, diagnosis, or care; (3) physical injury to any individual; (4) a threat to public health or safety; or (5) damage affecting a computer system used by or for a government entity in furtherance of the administration of justice, national defense, or national security.

Includes as a conviction for another offense, with respect to the investigative authority of the U.S. Secret Service, conviction for a crime punishable for more than one year which involves unauthorized access to a computer.

Amends the Communications Act of 1934 to make punishable under the Federal criminal code the intent to cause the unavailability of a communication device or interactive computer service, to cause damage to a protected computer, or to cause other persons to initiate such activities.

Makes it unlawful to intercept or access a wire or electronic communication configured to be readily accessible to the general public. Prohibits using evidence of unauthorized intercepted communications.

Provides: (1) increased protections from unlawful access to electronically stored communications; and (2) requirements for governmental access to such information.

Revises generally the authority for installing and using pen registers and trap and trade devices.