Medicare Certified Registered Nurse First Assistant Direct Reimbursement Act of 2000 - Amends title XVIII (Medicare) of the Social Security Act to provide for coverage of surgical first assisting services furnished by certified registered nurse first assistants.

Provides for payment of such nurses on an assignment-related basis.

Excludes services of such nurses from the definition of "covered skilled nursing facility services" for purposes of applying a prospective payment formula for such services.

Directs the Secretary of Health and Human Services to reduce the amount of Medicare payments otherwise made to hospitals to eliminate estimated duplicate payments for historical or current costs attributable to surgical first assisting services furnished by certified registered nurse first assistants.

Requires the Secretary to report to Congress on recommendations for adjustments to the payment amounts established under part B (Supplementary Medical Insurance) of Medicare for surgical first assisting services furnished by such nurses to ensure that the payment amounts reflect the approximate costs of furnishing such services, taking into account the costs of compensation, overhead, and supervision attributable to such nurses.